Glossary · Definition · v2026.3
What Is Luteal Phase Support?
Luteal support refers to the administration of progesterone and sometimes estrogen after egg retrieval or before frozen embryo transfer to prepare and maintain the uterine lining for embryo implantation.
Clinical significance
During IVF, the egg retrieval procedure removes granulosa cells along with the eggs, which can impair natural progesterone production by the corpus luteum. Luteal support compensates for this deficiency and is continued until the placenta produces sufficient progesterone on its own, typically around 8 to 10 weeks of pregnancy.
Common confusion
Luteal support is not optional in IVF: it is a standard part of the protocol. Stopping progesterone too early can lead to implantation failure or early pregnancy loss.
Related reference
Used in
This content defines terminology for educational orientation. It does not constitute medical advice.
IVF Daddies Newsletter
Structural briefings on policy, clinical, and regulatory developments.
Weekly updates on family-building governance.