Glossary · Definition · v2026.3
What Is Embryo Fragmentation?
Embryo fragmentation refers to small membrane-bound cellular debris that separates from blastomeres during early embryo development. Fragmentation is one of the key morphological criteria used in embryo grading.
Clinical significance
Mild fragmentation (less than 10%) is common and generally does not significantly reduce implantation potential. Moderate to severe fragmentation (greater than 25%) is associated with reduced embryo viability and lower pregnancy rates.
Common confusion
Fragmentation is not the same as cell division. Fragments are non-cellular debris, not functional blastomeres, and cannot contribute to embryo development.
Related reference
Used in
This content defines terminology for educational orientation. It does not constitute medical advice.
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