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    Glossary · Definition · v2026.3

    What Is Ovarian Suppression?

    Ovarian suppression is the use of medications to temporarily shut down the body's natural hormone signals that control the menstrual cycle, preventing premature ovulation during IVF stimulation.

    Clinical significance

    Ovarian suppression is achieved using GnRH agonists (long protocol) or GnRH antagonists (short protocol). Without suppression, the natural LH surge could trigger ovulation before egg retrieval, resulting in a cancelled cycle. The choice of suppression protocol depends on patient age, ovarian reserve, and prior cycle response.

    Common confusion

    Ovarian suppression is temporary and reversible. It does not permanently affect fertility or reduce ovarian reserve. Normal menstrual function resumes after medications are discontinued.

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    This content defines terminology for educational orientation. It does not constitute medical advice.

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