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Fertility · Clinical Education · v2026.3
What Is the IVF Success Rate?
Definition
IVF Success Rate is defined as: the probability of achieving a live birth through in vitro fertilization. Success is measured either per transfer cycle (live birth rate, or LBR) or cumulatively across all transfers from a single egg retrieval (cumulative live birth rate, or CLBR). Age is the single strongest predictor.
IVF success depends on how you define it. A per-cycle live birth rate gives one number. A cumulative live birth rate: which accounts for all embryos banked from one retrieval, gives a fundamentally different, usually higher, number. Understanding which metric a clinic reports is essential for accurate comparison.
Author: Julio Gaggia
Per-Transfer Live Birth Rate
The per-transfer live birth rate measures the probability of a live birth from a single embryo transfer. According to SART data, this ranges from approximately 45–50% for patients under 35 to under 15% for patients over 42. A single transfer with a PGT-A-screened euploid embryo has higher per-transfer success than an unscreened transfer.
Cumulative Live Birth Rate
Cumulative live birth rate (CLBR) captures the total probability of a live birth from all embryos produced in one retrieval cycle. If a retrieval yields three euploid blastocysts and each transfer has a 50% success rate, the cumulative probability of at least one live birth exceeds 85%. CLBR is the most clinically meaningful metric for patients planning IVF.
What Drives the Difference
Age drives the gap between per-cycle and cumulative rates. Younger patients produce more eggs, more blastocysts, and more euploid embryos per retrieval, increasing both per-cycle and cumulative success. Attrition at each stage of the funnel compounds the effect of age on outcomes.
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Sources
- Society for Assisted Reproductive Technology (SART) national reports, https://www.sart.org
- Human Fertilisation and Embryology Authority (HFEA) statistics, https://www.hfea.gov.uk
- European Society of Human Reproduction and Embryology (ESHRE), https://www.eshre.eu